Biofabrication for Regenerative Medicine

About

The Moroni Lab is part of the MERLN institute for Technology-Inspired Regenerative Medicine at Maastricht University, the Netherlands. The research group was founded in 2009 at University of Twente, the Netherlands, laying down its roots on biofabrication technologies to control cell fate. Today, the Moroni Lab has several local and international collaborations. Locally, we contribute to the Brightlands ecosystem, with which a new program on 3D printing for biomedical applications is being established. The vicinity of the Maastricht University academic hospital further facilitates strong collaborations with clinical departments. Internationally, we are active within the International Society for Biofabrication, the Tissue Engineering and Regenerative Medicine International Society, and the European Society for Biomaterials. Thanks to these communities, several collaborations are in place around the world. Current research projects are running thanks to National and European grants, among which an ERC starting grant to Professor Moroni, European consortia (H2020-FAST, and FP7-STELLAR), and regional funding investing in knowledge and innovation.

Latest News

Integrating Biofabrication Technologies

Unlocking the secrets of osteochondral regeneration has long been a daunting challenge, with the intricate interplay between cartilage and bone presenting formidable hurdles. However, a groundbreaking approach is on the horizon, poised to redefine the landscape of tissue regeneration: multiphasic scaffolds – the cornerstone of cutting-edge strategies aimed at mirroring the complexities of the osteochondral unit and nurturing the growth of implanted bone-marrow derived stem cells (BMSCs). Yet, amidst the promise, hurdles remain. Stem cell loss during expansion in vitro and the limited control over their behavior within scaffolds both in vitro and in vivo pose formidable challenges.

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Bioprinting in Space

In a new Pathfinder Open project, PULSE, we have partnered with different experts in space technology and use thereof to study how the Space environment could be working as an accelerator of ageing…

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New Hybrid Biofabrication technology

Many tissues in our body display gradients. These are not only biological gradients, but also structural, physical, and chemical ones, resulting in smoother variations of mechanical properties and cell functional activity.

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Kidney 3D in vitro models through bioprinting

At the Complex Tissue Regeneration department, we work hard to bridge the gap towards the dream of organs bioprinting. Step by step, we are now progressing towards understanding more and more in depth the requirements to bioprint different kidney cells, either derived from pluripotent stem cells or of adult species.

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Sponsorship

The major aim of our lab is to develop innovative biofarication approaches for regenerative medicine as well as training next generation's talented students and postdocs.

One of the most direct ways of contributing to these causes is by donating towards a research aim or sponsoring any of our group members directly. Please contact Professor Moroni about donations towards research for fighting diseases such as osteoarthritis, cardiovascular, and neural degeneration.

We are greatful to our generous sponsors!

BioFabrication for Medicine

We create solutions for clinical problems

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